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1) "Leptin" -- As to leptin lep·tin
Pronunciation: 'lep-t&n
Function: noun
Etymology: Greek leptos slender + English 1-in
: a peptide hormone that is produced by fat cells and plays a role in body weight regulation by acting on the hypothalamus to suppress appetite and burn fat stored in adipose tissue Pronunciation Symbols
| | | Identifiers | | Symbol(s) | LEP OBS, OB | | Entrez | 3952 | | OMIM | 164160 | | RefSeq | NM_000230 | | UniProt | P41159 | | Other data | | Locus | Chr. 7 q31 | | | | Identifiers | | Symbol(s) | LEPR | | Entrez | 3953 | | OMIM | 601007 | | RefSeq | NM_002303 | | UniProt | P48357 | | Other data | | Locus | Chr. 1 p31 | Leptin (from the Greek word leptos, meaning thin) is a 16 kDa protein hormone that plays a key role in regulating energy intake and energy expenditure, including the regulation of appetite and metabolism. The effects of leptin were observed by studying mutant obese mice that arose at random within a mouse colony at the Jackson Laboratory in 1950. These mice were massively obese and hyperphagic. Leptin itself was discovered in 1994 by Jeffrey M. Friedman..."
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